1

DEVELOPMENT OF LOCAL ANTIDOTE FORMULATION

VIEW INFOGRAPHICS

Research

"THIS PROJECT ADDRESSES THE CRITICAL NEED FOR NATIONAL HEALTH SECURITY BY DEVELOPING A LOCALLY PRODUCED ANTIDOTE FORMULATION FOR THE TREATMENT OF ORGANOPHOSPHATE (OP) POISONING AND CHEMICAL WARFARE AGENT (CWA) EXPOSURE. ORGANOPHOSPHATE COMPOUNDS ARE WIDELY USED AS AGRICULTURAL PESTICIDES AND ARE ALSO THE BASIS OF HIGHLY TOXIC NERVE AGENTS. ALTHOUGH EFFECTIVE MEDICAL COUNTERMEASURES ARE AVAILABLE, DEPENDENCE ON IMPORTED ANTIDOTE SUPPLIES AND INTERNATIONAL SUPPLY CHAINS CREATES STRATEGIC VULNERABILITIES DURING PUBLIC HEALTH EMERGENCIES, INDUSTRIAL ACCIDENTS, AGRICULTURAL POISONING INCIDENTS, AND POTENTIAL CHEMICAL WARFARE SCENARIOS. THE MAIN OBJECTIVE OF THIS PROJECT IS TO ESTABLISH LOCAL EXPERTISE IN ANTIDOTE FORMULATION DEVELOPMENT. THE RESEARCH WILL FOCUS ON IMPROVING FORMULATION PERFORMANCE, EXPLORING ALTERNATIVE ADMINISTRATION ROUTES SUCH AS TRANSDERMAL AND INTRANASAL DELIVERY, AND DEVELOPING USER-FRIENDLY DELIVERY SYSTEMS FOR RAPID ADMINISTRATION IN BOTH CIVILIAN AND MILITARY SETTINGS. THE EXPECTED OUTCOME IS A SELF-RELIANT NATIONAL CAPABILITY FOR PRODUCING EFFECTIVE ANTIDOTE FORMULATIONS, ENABLING TIMELY TREATMENT OF OP POISONING AND NERVE AGENT EXPOSURE, IMPROVING PATIENT SURVIVAL, AND STRENGTHENING MALAYSIA'S PREPAREDNESS AGAINST CHEMICAL EMERGENCIES. "

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RM500,000.00

VIEW

2

 

BEE-YOND AUTHENTICATION: KPRIX QUALITY MEETS SALMAH VALIDATION

VIEW INFOGRAPHICS

IP

OVER EIGHT YEARS OF MULTIDISCIPLINARY RESEARCH INTEGRATING FOOD CHEMISTRY, METABOLOMICS, BEE ECOLOGY, AND PLANT SCIENCES HAS LED TO THE DEVELOPMENT OF THE KELULUT PURITY & QUALITY INDEX (KPRIX) — A SCIENTIFICALLY VALIDATED FRAMEWORK FOR ASSESSING STINGLESS BEE HONEY QUALITY. KPRIX PARAMETERS ENCOMPASS SUGAR COMPOSITION, ANTIOXIDANT CAPACITY, ORGANIC ACIDS, MINERALS, MICROBIOTA, AND INDICATORS OF ADULTERATION, FORMING THE FOUNDATION FOR TRANSLATIONAL STUDIES UNDER THE SALMAH PROJECT (STINGLESS BEE HONEY ACTIVE LEAD COMPOUNDS WITH MEASURABLE EFFECTS IN ANTI‑DIABETIC HUMAN PRE‑CLINICAL STUDY). THE SALMAH TRIAL EVALUATES THE EFFECTS OF HONEY WITH VARYING KPRIX SCORES IN PREDIABETIC PARTICIPANTS ON GLYCEMIC AND METABOLIC OUTCOMES. TOGETHER, THESE INITIATIVES BRIDGE ECOSYSTEM‑BASED HONEY PROFILING WITH HUMAN HEALTH VALIDATION, ADVANCING MALAYSIA’S LEADERSHIP IN HALAL FUNCTIONAL FOOD INNOVATION. SUPPORTED BY NPRA PRE‑CLINICAL APPROVAL AND JAKIM HALAL CERTIFICATION, THIS INTEGRATED RESEARCH PIPELINE DEMONSTRATES A MODEL FOR SUSTAINABLE, EVIDENCE‑BASED COMMERCIALISATION OF STINGLESS BEE HONEY.

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RM660,000.00

VIEW

3

 

PROJECT STINGLESS BEE SMART HIVE EDUCATION

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IP

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RM157,700.00

VIEW

4

 

ICOMPBAG

VIEW INFOGRAPHICS

IP

ICOMPBAG (INFLATABLE COMPACT POSITIONING BAG) IS AN INNOVATIVE, LOCALLY DEVELOPED INFLATABLE POSITIONING DEVICE THAT PROVIDES STABLE, ADJUSTABLE, AND ERGONOMIC PATIENT POSITIONING FOR SURGERY, RADIOLOGY PROCEDURES (INCLUDING BREAST BIOPSY AND THYROID FNAC), AND REHABILITATION. LIGHTWEIGHT, REUSABLE, STERILIZABLE, AND EASILY PORTABLE, IT IMPROVES PROCEDURAL EFFICIENCY WHILE REDUCING MANUAL HANDLING AND LOGISTICAL CHALLENGES. DESIGNED TO REPLACE BULKY CONVENTIONAL POSITIONING DEVICES, ICOMPBAG OFFERS A COST-EFFECTIVE, SUSTAINABLE SOLUTION WITH STRONG COMMERCIAL POTENTIAL FOR HOSPITALS, AMBULATORY CARE, DEFENCE HEALTHCARE, AND REHABILITATION CENTRES, MAKING IT AN ATTRACTIVE OPPORTUNITY FOR INDUSTRY COLLABORATION AND INVESTMENT.

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RM100,000.00

VIEW

5

 

PREDICTION OF THE NEWTONIAN OF PREFERENTIAL FLOW IN THE GAS MASK FILTER IN MALAYSIA'S CLIMATE ENVIRONMENT

VIEW INFOGRAPHICS

Research

"THIS RESEARCH INNOVATES PROTECTIVE EQUIPMENT BY INTEGRATING ADVANCED COMPUTATIONAL FLUID DYNAMICS (ANSYS FLUENT) AND CAD MODELING WITH EXPERIMENTAL VALIDATION TO ANALYZE AERODYNAMIC FLOW PATTERNS UNDER MALAYSIA'S UNIQUE HIGH-HUMIDITY CONDITIONS. THE OBJECTIVES ARE TO EVALUATE FILTER EFFICIENCY ACROSS VARYING HUMIDITY LEVELS, QUANTIFY POLLUTANT IMPACTS ON FILTER LIFESPAN, AND OPTIMIZE AERODYNAMIC DESIGN PARAMETERS. EXPECTED OUTCOMES INCLUDE DURABLE, CLIMATE-OPTIMIZED GAS MASK FILTERS, ENHANCED WORKER SAFETY, AND UPGRADED DOSH-SIRIM CERTIFICATION STANDARDS. ULTIMATELY, THIS DELIVERS SUSTAINABLE, COST-EFFECTIVE SOLUTIONS THAT IMPROVE OCCUPATIONAL HEALTH AND REDUCE INDUSTRIAL WASTE"

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RM150,000.00

VIEW